Biologics

OBJECTIVE: To assess the geometry of canine humeri as seen on radiographs in chondrodystrophic dogs (CD) and brachycephalic dogs (BD) compared to non-chondrodystrophic dogs (NCD).

METHODS: Mediolateral (ML) and craniocaudal (CC) radiographs of skeletally mature humeri were used (CD [n = 5], BD [n = 9], NCD [n = 48]) to evaluate general dimensions (length, width, canal flare, cortical thickness), curvature (shaft, humeral head, and glenoid), and angulation (humeral head and condyle). Measurements from CD, BD, and NCD were compared.

Category: Biologics

OBJECTIVE: To assess the geometry of canine humeri as seen on radiographs in chondrodystrophic dogs (CD) and brachycephalic dogs (BD) compared to non-chondrodystrophic dogs (NCD).

METHODS: Mediolateral (ML) and craniocaudal (CC) radiographs of skeletally mature humeri were used (CD [n = 5], BD [n = 9], NCD [n = 48]) to evaluate general dimensions (length, width, canal flare, cortical thickness), curvature (shaft, humeral head, and glenoid), and angulation (humeral head and condyle). Measurements from CD, BD, and NCD were compared.

Category: Biologics

OBJECTIVE: To compare the antibacterial efficacy of different surgical hand antisepsis protocols used by veterinary students.

STUDY DESIGN: Prospective, randomized, controlled study.

STUDY POPULATION: Third year veterinary students (n=45).

Category: Biologics

OBJECTIVE: To investigate the frequency, source, and risk factors of intraoperative (IO) surgeon and patient bacterial contamination during clean orthopedic surgeries, and to investigate the relationship between IO contamination and surgical site infection (SSI) in dogs.

STUDY DESIGN: Prospective clinical study.

SAMPLE POPULATION: Client-owned dogs undergoing stifle surgery (n = 100).

Category: Biologics

OBJECTIVE: To evaluate blood coagulation using thromboelastometry in dogs following orthopedic surgery.

DESIGN: Longitudinal observational study.

SETTING:  University veterinary teaching hospital.

ANIMALS:  Thirty-four adult client-owned dogs.

Category: Biologics
Authors: Minier K1, Touré A, Fusellier M, Fellah B, Bouvy B, Weiss P, Gauthier O.
Journal: VCOT

OBJECTIVES:

To determine whether the addition of recombinant human bone morphogenetic protein (rhBMP-2) to a self-crosslinkable cellulosic hydrogel/biphasic calcium phosphate (BCP) granules construct promotes bone healing in critical-size ulnar defects in dogs.

METHODS:

Authors: Walton MB1, Mardell E, Spoor M, Innes J.
Journal: VCOT

A four-year-old, male Cocker Spaniel was presented for investigation of pelvic limb stiffness. There was palpable effusion of both tarsi, and analysis of synovial fluid from these joints indicated previous haemorrhage. After further investigation a diagnosis of idiopathic immune-mediated thrombocytopenia was made. The dog responded to treatment with prednisolone and azathioprine. To the authors' knowledge, this is the first reported case of confirmed haemarthrosis as the sole presenting clinical sign for canine idiopathic immune-mediated thrombocytopenia.

Category: Biologics - Hock
Authors: Nicoll C1, Singh A, Weese JS.
Journal: Vet Surg

OBJECTIVE:

To evaluate the economic impact of surgical site infection after tibial plateau leveling osteotomy (TPLO) in dogs.

STUDY DESIGN:

Retrospective study

STUDY POPULATION:

Dogs that had unilateral TPLO and did (n = 32) or did not (controls; 32) develop a surgical site infection.

METHODS:

Medical and billing records were reviewed to identify postoperative care and costs, which were compared between groups.

RESULTS:

Authors: Nazarali A1, Singh A, Weese JS.
Journal: Vet Surg

Abstract

OBJECTIVE:

To evaluate perioperative antimicrobial administration during tibial plateau leveling osteotomy (TPLO) in dogs at the Ontario Veterinary College Health Sciences Centre.

STUDY DESIGN:

Retrospective case series.

ANIMALS:

Dogs (n = 184) that had TPLO (n = 226).

METHODS:

Category: Biologics - Knee
Authors: Hilligas J1, Van Wie E, Barr J, Russell KE, Perry AL, Weeks BR, Zhang S.
Journal: J Vet Intern Med

No Abs

Category: Biologics - Spine